A Dramatic New Concept in High Resolution, Inverted Fluorescence Microscopy

Lumascopes are highly versatile, compact inverted fluorescence microscopes that provides high resolution images comparable to those from traditional, high-cost microscopes. The Lumascope design was conceived and developed by working scientists who realized that a large proportion of everyday fluorescence microscopy involves imaging and measuring the presence, health, and signal of labeled cells. Traditional inverted microscopes are expensive, complicated, and loaded with features that are not required for these tasks. Lumascopes focus on: quality images, versatility, compact design, ease of use, and amazingly low price.

Lumascopes utilize LED light sources, Semrock filters, advanced optical engineering, and CMOS sensors to provide near diffraction-limited (theoretical maximum) resolution. Powered only by a USB connection, Lumascopes easily record your photos, time-lapse series, and live videos directly to your computer. And their compact size enable working in challenging locations, including inside incubators, biological safety cabinets, and environmental control workstations with remote control and image monitoring.

The inverted design accommodates microplates, flasks, dishes and custom labware in addition to slides that you can adjust by the Manual XY Stage (on the Lumascopes 620, 560 or 460; sold separately) or control manually or automatically on the automated Lumascope 720. Lumascopes come with Lumaview software that sends images directly to your computer via a USB cable, eliminating the need for on-board image storage and processing and contributing to the compact size. Lumaview enables time-lapse studies over seconds, minutes, hours, or days. Live videos can be recorded at up to 30 frames per second.

Lumascopes Can Be Used in Many Applications

  • Live cell imaging

  • Cell growth and confluence

  • Cell migration and wound healing

  • Determining transfection efficiency

  • Tracking and quantifying protein expression

  • Following cell differentiation

  • High Content Analysis

  • Intravital studies

  • Photomicroscopy in locations without AC power

 

Etaluma - LS720 Microscope

The LS720 offers a whole new world of automated microscopy.

Blue, Green, & Red Fluorescence and Walk-Away Automation

The powerful, new LS720 Microscope adds walk-away automation to the many features and high performance of the flagship 3-color LS620. Exquisite XY motion control, motorized focus that allows autofocus and z-stacks, and easy-to-configure software combine to facilitate your microscopy experiments and high content screens. Place the LS720 in your incubator and you have a live cell imaging system at a fraction of the cost of conventional High Content Analysis systems. Whether imaging multiple fields in your flasks or 1536 wells of cells with 3 fluorophores in a 48 hour time-lapse, the LS720 offers a whole new world of automated microscopy!

Features and Benefits

  • Automated XY stage with autofocus in Z provides images (photos), time-lapse series, and videos recorded directly to your computer
  • Fully functioning microscope empowers users to visualize cells from microplates, flasks, slides or custom labware
  • Modern LED and advanced optical design provide near diffraction-limited (theoretical maximum) resolution
  • Robust software allows set-up and control across many locations, including microplates and custom arrays
  • Versatile and compact design enables use inside cell culture incubators and hoods
  • Detects blue, green and red fluorophores, including BFP, DAPI, FITC, Fluo-4, GFP & mCherry
  • Flip-up deck allows easy objective access
  • Used manually, but also robot compatible (RS485, RS232, 5V digital interfaces)
  • Objective compatibility with standard lenses permits use of your own objectives
Like the LS620, the LS720 utilizes a Semrock Brightline® Pinkel filter set optimized for 405 nm, 488 nm, and 594 nm LED light sources. The 5-filter set is comprised of 3 exciting filters, 1 triple-band emitting filter, and 1 beam-splitting filter. The 720 also contains the same CMOS sensor as the LS620.
 
 
Etaluma - LS620 Microscope

The LS620 easily records your photos, time-lapse series, and videos directly to your computer.

Blue, Green, and Red Fluorescence, Brightfield, and Optional Phase Contrast

Use the LS620 to visualize and capture high resolution fluorescence images comparable to those from traditional, high-cost microscopes. LS Microscopes utilize LED light sources, Semrock filters, advanced optical engineering, and CMOS sensors to provide near diffraction-limited (theoretical maximum) resolution. Powered only by its USB connection, the LS620 easily records your photos, time-lapse series, and live videos directly to your computer. And its compact size enables working in challenging locations, including inside incubators, biological safety cabinets, and environmental control workstations. The LS620 provides blue, green and red fluorescence imaging at low cost for a wide variety of applications!

Features and Benefits

  • Fully functioning microscope empowers users to visualize cells from slides, microplates, flasks, or dishes
  • Versatile and compact design permits use inside cell culture incubators, tissue culture hoods, and environmental workstations
  • Robust software enables time-lapse studies over seconds, minutes, hours, or days
  • Modern LED and optical design lowers cost and eliminates cumbersome, difficult to maintain laser-driven and arc lamp systems
  • Power and control via USB connection facilitates rapid set up and easy use
  • Custom optimized filter set detects a range of blue, green and red fluorophores, including BFP, DAPI, FITC, Fluo-4, GFP, and mCherry
  • Advanced optics provide excellent resolution in ambient lighting conditions
  • Objective compatibility with standard lenses allows use of your own objectives
  • Optional Phase Contrast Accessory enhances visualization of unstained samples

The LS620 is the most powerful digital microscope offered anywhere at this price. Like the earlier LS600, it utilizes a Semrock Brightline® Pinkel filter set optimized for 405 nm, 488 nm, and 594 nm LED light sources. The 5-filter set is comprised of 3 exciting filters, 1 triple-band emitting filter, and 1 beam-splitting filter. The LS620 also contains the same CMOS sensor as the LS600 that is larger than the sensor used in LS520 and LS420.

Etaluma - LS560 Microscope

Powered only by its USB computer connection, the LS560 easily records your photos, time-lapse series, and videos directly to your computer.

Green Fluorescence, Brightfield, and Optional Phase Contrast

Use the LS560 Microscope to visualize and capture high resolution widefield images comparable to those from traditional, high-cost microscopes. The LS560 utilizes an LED light source, Semrock filters, advanced optical engineering, and a CMOS sensor to provide near diffraction-limited (theoretical maximum) resolution. Powered only by a direct USB computer connection, the LS560 uses the same USB cable to send your photos, time-lapse series, and videos directly to your computer. And its compact size enables working inside challenging locations including incubators , hoods, and environmental chambers.

The new LS560 has an improved camera and optics plus a C-mount compared to the previous LS520 model, plus the accessible deck and improved phase contrast (optional) introduced in the LS520.

Features and Benefits

  • Digital inverted microscope compatible with microplates, slides, flasks, dishes, microfluidic chips, custom labware
  • Compact design and environmentally rugged; use in incubators, hoods, and environmental chambers over months
  • Comes with Lumaview software for capture of images, time-lapse series, and live video
  • Simple USB connection to your computer provides power and control
  • Excellent resolution in ambient lighting conditions or with Phase Contrast Accessory
  • Detects green fluorophores, including FITC, Fluo-4 and GFP
  • Includes accessible deck for easy exchange of objectives
  • Optional Phase Contrast Accessory (Olympus condenser) for imaging of unstained samples
The LS560 utilizes a Semrock Brightline®Basic filter set optimized for FITC and other similar fluorophores. The 3-filter set is comprised of 1 excitation filter, 1 emission filter, and 1 beam-splitting filter. The LS560 contains a high sensitivity monochrome CMOS sensor with a 1700×1700 pixel image. Because the emission filter is limited to 508-552 nanometers, brightfield images are monochromatic.
Etaluma - LS460 Microscope

The LS460 microscope’s advanced optics provide excellent resolution in ambient lighting conditions

Monochrome Brightfield and Optional Phase Contrast

The LS460 Microscope provides monochrome brightfield imaging at low cost for a wide variety of applications. LS Microscopes visualize and capture high resolution images comparable to those from traditional, high-cost microscopes. The LS460 utilizes advanced optical engineering and a CMOS sensor to provide near diffraction-limited (theoretical maximum) resolution. Powered only by its USB computer connection, the LS460 easily records your photos, time-lapse series, and videos directly to your computer. And its compact size enables working in challenging locations, including inside incubators, biological safety cabinets, and environmental control workstations.

The LS460 is the new upgraded version in the Etaluma LS400-Series. Its deck includes the bracket for the optional Phase Contrast Accessory and also the accessible deck design.

Features and Benefits

  • Fully functioning microscope empowers users to visualize cells from slides, microplates, flasks, or dishes
  • Versatile and compact design permits use inside cell culture incubators, tissue culture hoods, and environmental workstations
  • Robust software enables time-lapse studies over seconds, minutes, hours, or days
  • Power and control via USB connection facilitates rapid set up and easy use
  • Advanced optics provide excellent resolution in ambient lighting conditions
  • Objective compatibility with standard lenses allows use of your own objectives
  • Optional Phase Contrast Accessory enhances visualization of unstained samples

The LS460 contains a high sensitivity CMOS sensor with a 100×100 to 1700×1700 pixel image.

The LS460 comes with the new standardized deck that includes both the tab for mounting the Phase Contrast Accessory and the removable insert for easy objective change. On the underside of the left end of the deck are 2 tapped holes for mounting the optional Manual XY Stage (see Optional Accessories below).

The LS460 also comes with a USB power/communication cable for connecting to a computer.

The LS460 is controlled by Lumaview software that can be downloaded at no charge from the Etaluma website (see Resources/Downloads).

Objectives are sold separately (see Products/Objectives).