A Compounding Aseptic Containment Isolator (CACI) designed for the containment of hazardous chemotherapy and other agents and IV admixtures ChemoSHIELD® negative pressure compounding aseptic containment isolators offer a contained, leak-tight (tested to AGS standard), negative pressure work area suitable for hazardous pharmaceutical compounds, chemotherapy agents or IV admixtures that can be harmful to pharmacy personnel. ChemoSHIELD creates a unidirectional HEPA-filtered airflow of better than ISO Class 5 (Class 100) air cleanliness conditions within the negative pressure chamber to prevent migration of hazardous contaminants to the outside and to minimize cross-contamination across the direct compounding area. ChemoSHIELD has no onboard motor/blower to maintain and service. All static pressure and airflow are supplied by the building exhaust system.